Citicoline (CDP-Choline) – Powder (20g)

$18.99

✓ High quality reference material

✓ Contains 20g per jar

This material is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please familiarize yourself with our Terms & Conditions prior to ordering.

83 in stock (can be backordered)

ApplicationNootropic
CAS987-78-0
Molar Mass489.33 g/mol
Chemical FormulaC14H27N4O11P2+
IUPAC Name2-[[[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxyethyl-trimethylazanium
SynonymsCiticoline, CDP-choline, DTXSID9048431, ZINC6507065, 987C780, Q421308, 5′-Diphosphocholine, Cytidine, Cytidine Diphosphate, Cidifos, Citicholine, Cyticholine, Cytidine 5′ Diphosphocholine, Cytidine 5′-Diphosphocholine, Cytidine Diphosphate Choline, Diphosphate Choline
StorageStore at room temperature, tightly sealed, away from heat, light and moisture.
SolubilitySoluble in Methanol, Ethanol, Acetone, Water
Organoleptic ProfileWhite Powder
Physical FormPowder
SpecificationPurity 99%+. Chemical analysis available on request.

Buy Citicoline (CDP-Choline) | Choline source | Read more:

Background

Citicoline is held in high regard as one of the best choline sources.[1] Choline, once an acetyl group is donated to it, forms acetylcholine which is an important neurotransmitter for memory. This is how Citicoline improves learning in aged volunteers.[2] What separates Citicoline or CDP-Choline from other choline sources is that it’s less likely to generate TMAO,[1] which is known to be associated with heart failure. This is why Alpha-GPC, but not Citicoline increased stroke risk by 800%.[3] Choline is an important dietary nutrient that some are deficient in, and acetylcholine is a primary target in preventing Alzheimer’s. Increasing acetylcholine has been shown to enhance the memory improvement by other nootropics, such as Tropisetron and Piracetam. We hope to encourage research by allowing researchers to buy Citicoline.

Pharmacokinetics

Citicoline’s oral bioavailability is nearly 100%, and it is well absorbed.

References

[1] Citicoline is less likely to generate TMAO: https://pubmed.ncbi.nlm.nih.gov/31336819/

[2] Citicoline improves cognition in aged volunteers: https://pubmed.ncbi.nlm.nih.gov/8624220/

[3] Alpha-GPC causes risk for stroke: https://pubmed.ncbi.nlm.nih.gov/34817582/

[4] CDP-Choline oral bioavailability: https://pubmed.ncbi.nlm.nih.gov/6684463/

Disclaimer

Scientific discussion is purely for educational purposes. This is not medical advice.


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