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Background
Tabernanthalog (TBG) is an Ibogaine derivative. Despite this, TBG lacks recreational value as well as hallucinogenic effects, separating it from the analogue act. This is evidenced by a lack of head twitch in rodent models.[1] TBG lacks concrete data elucidating its mechanisms, but it is thought to influence neurogenesis similarly to a psychedelic.[1] So far, TBG appears a promising candidate both for substance abuse disorders and depression.[2]
References
[1] Tabernanthalog does not induce head twitch, rescues mice from stress. Neurogenic cause: https://www.nature.com/articles/s41380-021-01159-1
[2] Tabernanthalog for substance abuse and depression: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874389/
Disclaimer
Scientific discussion is purely for educational purposes. This is not medical advice.
