NSI-189 Freebase – Solution (40mg/mL)


✓ High quality reference material

✓ Approximately 20mg per 0.5mL

✓ Contains 30mL per bottle (1200mg NSI-189 Freebase)

✓ Estimated 30 days of research supply

Out of stock


NSI-189 is a acts on glucocorticoid receptors, separating it from other candidates tried for depression (which are primarily serotonergic). It was tried due to findings of decreased hippocampal growth in depressed patients, which NSI-189 would in theory remedy due to its neurotrophic effects. It had success in early trials, but ultimately failed later on. Still new interest is sparked in this compound due to its potential nootropic effects.


Scientific discussion is purely for educational purposes. This is not medical advice.

Molar Mass366.5 g/mol
Chemical FormulaC22H30N4O
IUPAC Name(4-benzylpiperazin-1-yl)(2-(isopentylamino)pyridin-3-yl)methanone
SynonymsNSI189, NSI 189
StorageStore at room temperature, tightly sealed, away from heat, light and moisture.
SolubilitySoluble in Caprylic Acid
Organoleptic ProfileClear liquid
Physical FormLiquid, solved in Caprylic Acid
Specification40mg/mL±10% in 30mL, purity 99%+. Chemical analysis available on request.