NSI-189 Freebase – Solution (40mg/mL)


✓ High quality reference material

✓ Approximately 20mg per 0.5mL

✓ Contains 30mL per bottle (1200mg NSI-189 Freebase)

✓ Estimated 30 days of research supply

Application Neurotrophic
CAS 1270138-40-3
Molar Mass 366.5 g/mol
Chemical Formula C22H30N4O
IUPAC Name (4-benzylpiperazin-1-yl)(2-(isopentylamino)pyridin-3-yl)methanone
Synonyms NSI189, NSI 189
Storage Store at room temperature, tightly sealed, away from heat, light and moisture.
Solubility Soluble in Caprylic Acid
Organoleptic Profile Clear liquid
Physical Form Liquid, solved in Caprylic Acid
Specification 40mg/mL±10% in 30mL, purity 99%+. Chemical analysis available on request.
Terms This material is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please familiarize yourself with our Terms & Conditions prior to ordering.

21 in stock (can be backordered)


NSI-189 is a acts on glucocorticoid receptors, separating it from other candidates tried for depression (which are primarily serotonergic). It was tried due to findings of decreased hippocampal growth in depressed patients, which NSI-189 would in theory remedy due to its neurotrophic effects. It had success in early trials, but ultimately failed later on. Still new interest is sparked in this compound due to its potential nootropic effects.


Scientific discussion is purely for educational purposes. This is not medical advice.

Additional information

Weight 0.095485694 kg
Dimensions 3.175 × 3.175 × 10.795 cm