| Class | 5-HT3 antagonist, α7 nicotinic partial agonist |
|---|---|
| CAS | 89565-68-4 |
| Molar Mass | 284.35 g/mol |
| Chemical Formula | C17H20N2O2 |
| IUPAC Name | (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylate |
| Synonyms | Tropisetron, Tropisetronum, Novaban, UNII-6I819NIK1W, ICS 205930, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylate, CHEMBL56564, 6I819NIK1W, CHEBI:32269, 1alphaH,5alphaH-Tropan-3alpha-yl indole-3-carboxylate, Lopac-T-104, CAS-89565-68-4, NCGC00015984-03, NSC-759842, GTPL260, ics205-930 |
| Storage | Store at room temperature, tightly sealed, away from heat, light and moisture. |
| Solubility | Soluble in type-2 deionized water |
| Organoleptic Profile | Clear liquid |
| Physical Form | Liquid, solved in type-2 deionized water and sterilized with 0.1% potassium sorbate |
| Specification | 20mg/mL±10% in 10mL, purity 98%+. Chemical analysis available on request. |
Tropisetron HCl – Solution (20mg/mL)
$19.99
✓ High quality reference material
✓ Approximately 5mg per 0.25mL
✓ Contains 10mL per bottle (200mg Tropisetron HCl)
80 in stock (can be backordered)
Background
Tropisetron is a 5-HT3 receptor antagonist and a partial agonist at α7 nicotinic acetylcholine receptors. It is a registered pharmaceutical in several countries outside the US.
Pharmacology
α7 nicotinic partial agonism increases calcium influx while limiting hyperactivation of the receptor. 5-HT3 antagonism increases acetylcholine release.
Pharmacokinetics
Tropisetron’s oral bioavailability is about 60% and its half-life about 6 hours.
Research use only
For laboratory research use only. Not for human or animal consumption, or for any medical, diagnostic, therapeutic or recreational use.
